Melanoma Risk?

iStock_000005928967_Double-120x86Melanoma is a frightening prospect for most, and the number of people who develop it seems to increase all the time.  Now, as Rick and I discuss on PodMed this week, comes a study suggesting that certain citrus fruits, and very specific forms of said fruits, increase the risk of developing this most deadly form of skin cancer.??????? what? These fruits touted as beneficial might actually be detrimental?  Let's take a bit of a closer look at this study published in the Journal of Clinical Oncology.

The study combines data from the Nurses Health Study and the Health Professionals Follow-Up Study for a total of more than 100,000 subjects.  Lots of data has been gathered over decades in these vigilant folks, including dietary questionnaires and objective information such as disease development.  The long and short of it in this analysis is a relationship between melanoma development and consumption of grapefruits, but not grapefruit juice, and a less robust relationship between orange juice and the disease, but not whole oranges.  Hmmmm.  Certainly gives pause for contemplation if nothing else, along with speculation on differences in forms and fruits in the citrus family.  Rick and I agree that action points for now are non-existent, unless you're a researcher with money to examine this relationship prospectively.  Garnered lots of media attention, however.

Other topics this week include the diabetes drug liraglutide for obesity in NEJM, stroke treatment guidelines in Stroke, and a vaccine for Helicobacter pylori in the Lancet.  Until next week, y'all live well.

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