More Joy for Coffee Drinkers

UnknownCoffee drinkers have been on a bit of a roller coaster for some years, with studies seeming to conflict on the risk/benefit profile with respect to quaffing the beverage. Joy indeed then has come with a study in Annals of Internal Medicine Rick and I discuss on PodMed this week. Actually there are two of them, both huge in size and scope, and the take home is clear: if you drink coffee you don't have to worry about negative consequences of your habit, at least as long as it doesn't exceed a few cups a day.

One of the studies analyzed data from the European Prospective Investigation into Cancer and Nutrition study, following over 521,000 subjects. Relative to coffee consumption, the mean follow up was 16.4 years. During that time almost 42,000 deaths occurred, with an inverse relationship apparent with drinking coffee that did not vary by country or coffee preparation method. The second study looked at consumption of the beverage and mortality among non-white and some white individuals in the Multiethnic Cohort, comprising over 185,000 subjects. The same inverse relationship between coffee drinking and mortality was seen, whether death was due to heart disease, cancer, respiratory disease, stroke, diabetes, or kidney disease. The only subpopulation in whom the benefit wasn't as great was Hawaiian Americans. As I quip to Rick in the podcast, that's confirmation enough for me to continue my practice!

Other topics this week include Long-Term Results of the PIVOT Prostate-Cancer Trial and Diet Quality and Total and Cause-Specific Mortality in NEJM, and in JAMA,Effects of Antidepressant Switching vs Augmentation on Depression.

Also, here's the update on resistant HCV infection, as promised a couple of podcasts ago: http://www.journal-of-hepatology.eu/article/S0168-8278(17)30011-9/fulltext

Until next week, y'all live well.

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